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<wo-patent-document lang="it" status="Registered" country="SM">
  <wo-bibliographic-data status="Brevetto concesso">
    <application-reference>
      <document-id>
        <country>SM</country>
        <doc-number>T/2026/000169</doc-number>
        <date>20191217</date>
      </document-id>
    </application-reference>
    <priority-claims>
      <priority-claim sequence="0001" kind="national">
        <country>US</country>
        <doc-number>201862780667 P</doc-number>
        <date>20181217</date>
      </priority-claim>
    </priority-claims>
    <parties>
      <applicants>
        <applicant sequence="0001" app-type="applicant" designation="all">
          <addressbook lang="it">
            <name>VERTEX PHARMACEUTICALS INCORPORATED</name>
            <address>
              <address-1>50 Northern Avenue, Boston, MA 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
          <nationality>
            <country/>
          </nationality>
          <residence>
            <country>US</country>
          </residence>
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      </applicants>
      <inventors>
        <inventor sequence="0001">
          <addressbook lang="it">
            <name>MEDEK, Ales</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0002">
          <addressbook lang="it">
            <name>SHI, Yi</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0003">
          <addressbook lang="it">
            <name>GAGNON, Kevin</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0004">
          <addressbook lang="it">
            <name>WANG, Tiansheng</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0005">
          <addressbook lang="it">
            <name>KRUEGER, Elaine B.</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0006">
          <addressbook lang="it">
            <name>ROSE, Peter</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0007">
          <addressbook lang="it">
            <name>CAO, Jingrong</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0008">
          <addressbook lang="it">
            <name>COME, Jon H.</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="0009">
          <addressbook lang="it">
            <name>SAYEGH, Camil</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00010">
          <addressbook lang="it">
            <name>FORTIER, Anne</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00011">
          <addressbook lang="it">
            <name>HAMEL, Martine</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00012">
          <addressbook lang="it">
            <name>SENTER, Timothy J.</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00013">
          <addressbook lang="it">
            <name>BRODNEY, Michael</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00014">
          <addressbook lang="it">
            <name>WITKOS, Faith</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00015">
          <addressbook lang="it">
            <name>DORSCH, Warren A.</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00016">
          <addressbook lang="it">
            <name>LEDFORD, Brian</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00017">
          <addressbook lang="it">
            <name>NANTHAKUMAR, Suganthini S.</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00018">
          <addressbook lang="it">
            <name>NICOLAS, Olivier</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00019">
          <addressbook lang="it">
            <name>DENIS, Francois</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00020">
          <addressbook lang="it">
            <name>SHRESTHA, Muna</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00021">
          <addressbook lang="it">
            <name>HU, Kan-Nian</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
        <inventor sequence="00022">
          <addressbook lang="it">
            <name>DAKIN, Leslie A.</name>
            <address>
              <address-1>50 Northern Avenue, Boston, Massachusetts 02210, US</address-1>
              <country>US</country>
            </address>
          </addressbook>
        </inventor>
      </inventors>
      <agents>
        <agent sequence="0001" rep-type="agent">
          <addressbook lang="it">
            <name>DE BENEDETTI, Jacopo</name>
            <address>
              <address-1>Via L. Cibrario, 25, 47893 Borgo Maggiore RSM , SM</address-1>
              <country>SM</country>
            </address>
          </addressbook>
        </agent>
      </agents>
    </parties>
    <invention-title lang="it">INIBITORI DI APOL1 E METODI D’USO DEGLI STESSI</invention-title>
    <invention-title lang="en">INHIBITORS OF APOL1 AND METHODS OF USING SAME</invention-title>
    <wo-term-of-grant>
      <date>20260410</date>
      <doc-number>2026000169</doc-number>
    </wo-term-of-grant>
    <pct-or-regional-filing-data>
      <document-id>
        <country>19</country>
        <doc-number>PCT/19839496.7</doc-number>
        <date>20191217</date>
      </document-id>
    </pct-or-regional-filing-data>
    <pct-or-regional-publishing-data>
      <document-id>
        <country>EP</country>
        <doc-number>WO/3897833</doc-number>
        <date>20260204</date>
      </document-id>
    </pct-or-regional-publishing-data>
    <wo-national-office-event national-office-event-type="Filed" doc-number="SM/T/2026/000169" event-name="Filing">
      <wo-national-office-event-date>
        <date>20191217</date>
      </wo-national-office-event-date>
    </wo-national-office-event>
    <wo-national-office-event national-office-event-type="Registered" event-name="Brevetto EPO concesso">
      <wo-national-office-event-date>
        <date>20260410</date>
      </wo-national-office-event-date>
    </wo-national-office-event>
    <wo-national-office-filing-data appl-type="Brevetti EPO No.3897833    2026.02.04" file-type="T">
      <kind-of-protection>Brevetti EPO</kind-of-protection>
    </wo-national-office-filing-data>
  </wo-bibliographic-data>
</wo-patent-document>
